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BDBM50424327 CHEMBL2314501

SMILES: CN1CCCN(CC1)c1nc(N)nc2[nH]c(cc12)-c1ccccc1

InChI Key: InChIKey=NXYYLCZMJKQERA-UHFFFAOYSA-N

Data: 1 KI

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50424327   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histamine H4 receptor


(Homo sapiens (Human))
BDBM50424327
PNG
(CHEMBL2314501)
Show SMILES CN1CCCN(CC1)c1nc(N)nc2[nH]c(cc12)-c1ccccc1
Show InChI InChI=1S/C18H22N6/c1-23-8-5-9-24(11-10-23)17-14-12-15(13-6-3-2-4-7-13)20-16(14)21-18(19)22-17/h2-4,6-7,12H,5,8-11H2,1H3,(H3,19,20,21,22)
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KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
1.41E+3n/an/an/an/an/an/an/an/a



KU Leuven

Curated by ChEMBL


Assay Description
Displacement of [3H]Histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai/o and Gbeta1gamma


Bioorg Med Chem Lett 23: 132-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.10.139
BindingDB Entry DOI: 10.7270/Q28P61TF
More data for this
Ligand-Target Pair