BDBM50424337 CHEMBL2314775

SMILES: CN1CCN(CC1)c1nc(N)nc2[nH]c(cc12)-c1ccc(Cl)cc1

InChI Key: InChIKey=ONSVAYAAYDPLDK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50424337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50424337 (CHEMBL2314775) Show SMILES CN1CCN(CC1)c1nc(N)nc2[nH]c(cc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C17H19ClN6/c1-23-6-8-24(9-7-23)16-13-10-14(11-2-4-12(18)5-3-11)20-15(13)21-17(19)22-16/h2-5,10H,6-9H2,1H3,(H3,19,20,21,22)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.28E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Displacement of [3H]Histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai/o and Gbeta1gamma				Bioorg Med Chem Lett 23: 132-7 (2012) Article DOI: 10.1016/j.bmcl.2012.10.139 BindingDB Entry DOI: 10.7270/Q28P61TF
					More data for this Ligand-Target Pair