BDBM50424340 CHEMBL2314772

SMILES: Nc1nc(N2CCNCC2)c2cc([nH]c2n1)-c1ccccc1

InChI Key: InChIKey=KKQDGWSFNFRULV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50424340   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50424340 (CHEMBL2314772) Show SMILES Nc1nc(N2CCNCC2)c2cc([nH]c2n1)-c1ccccc1 Show InChI InChI=1S/C16H18N6/c17-16-20-14-12(15(21-16)22-8-6-18-7-9-22)10-13(19-14)11-4-2-1-3-5-11/h1-5,10,18H,6-9H2,(H3,17,19,20,21)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
KU Leuven Curated by ChEMBL					Assay Description Displacement of [3H]Histamine from human histamine H4 receptor expressed in Sf9 cells co-expressing Galphai/o and Gbeta1gamma				Bioorg Med Chem Lett 23: 132-7 (2012) Article DOI: 10.1016/j.bmcl.2012.10.139 BindingDB Entry DOI: 10.7270/Q28P61TF
					More data for this Ligand-Target Pair