null

SMILES: CN(C)Cc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCC2)c2ccccc12

InChI Key: InChIKey=HIQCZDGSCMKKFM-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50424463   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50424463 (CHEMBL2316407) Show SMILES CN(C)Cc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCC2)c2ccccc12 Show InChI InChI=1S/C25H28N4O2/c1-29(2)16-18-12-13-21(20-10-4-3-9-19(18)20)24(30)28-22-11-6-14-26-23(22)25(31)27-15-17-7-5-8-17/h3-4,6,9-14,17H,5,7-8,15-16H2,1-2H3,(H,27,31)(H,28,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	180	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Agonist activity at human CB1 receptor expressed in HEK293S cell membranes after 1 hr by GTPgamma[35S] binding assay				J Med Chem 56: 220-40 (2013) Article DOI: 10.1021/jm301511h BindingDB Entry DOI: 10.7270/Q2057H7B
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50424463 (CHEMBL2316407) Show SMILES CN(C)Cc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCC2)c2ccccc12 Show InChI InChI=1S/C25H28N4O2/c1-29(2)16-18-12-13-21(20-10-4-3-9-19(18)20)24(30)28-22-11-6-14-26-23(22)25(31)27-15-17-7-5-8-17/h3-4,6,9-14,17H,5,7-8,15-16H2,1-2H3,(H,27,31)(H,28,30)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-CP55,940 from human CB1 receptor expressed in HEK293S cell membranes by scintillation counting analysis				J Med Chem 56: 220-40 (2013) Article DOI: 10.1021/jm301511h BindingDB Entry DOI: 10.7270/Q2057H7B
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50424463 (CHEMBL2316407) Show SMILES CN(C)Cc1ccc(C(=O)Nc2cccnc2C(=O)NCC2CCC2)c2ccccc12 Show InChI InChI=1S/C25H28N4O2/c1-29(2)16-18-12-13-21(20-10-4-3-9-19(18)20)24(30)28-22-11-6-14-26-23(22)25(31)27-15-17-7-5-8-17/h3-4,6,9-14,17H,5,7-8,15-16H2,1-2H3,(H,27,31)(H,28,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Displacement of [3H]-CP55,940 from human CB2 receptor expressed in Sf9 cell membranes by scintillation counting analysis				J Med Chem 56: 220-40 (2013) Article DOI: 10.1021/jm301511h BindingDB Entry DOI: 10.7270/Q2057H7B
					More data for this Ligand-Target Pair