BDBM50425104 CHEMBL2312933

SMILES: CCCN(c1cccnc1)P(=O)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=PRXWWJUWFYAFRK-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50425104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50425104 (CHEMBL2312933) Show SMILES CCCN(c1cccnc1)P(=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C20H21N2OP/c1-2-16-22(18-10-9-15-21-17-18)24(23,19-11-5-3-6-12-19)20-13-7-4-8-14-20/h3-15,17H,2,16H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 23: 706-10 (2013) Article DOI: 10.1016/j.bmcl.2012.11.098 BindingDB Entry DOI: 10.7270/Q2H133BG
					More data for this Ligand-Target Pair
Voltage-gated potassium channel subunit Kv1.5 (Homo sapiens (Human))	BDBM50425104 (CHEMBL2312933) Show SMILES CCCN(c1cccnc1)P(=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C20H21N2OP/c1-2-16-22(18-10-9-15-21-17-18)24(23,19-11-5-3-6-12-19)20-13-7-4-8-14-20/h3-15,17H,2,16H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of human Kv1.5 channel expressed in CHO cells by high throughput planar patch clamp assay				Bioorg Med Chem Lett 23: 706-10 (2013) Article DOI: 10.1016/j.bmcl.2012.11.098 BindingDB Entry DOI: 10.7270/Q2H133BG
					More data for this Ligand-Target Pair
Intermediate conductance calcium-activated potassium channel protein 4 (Homo sapiens (Human))	BDBM50425104 (CHEMBL2312933) Show SMILES CCCN(c1cccnc1)P(=O)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C20H21N2OP/c1-2-16-22(18-10-9-15-21-17-18)24(23,19-11-5-3-6-12-19)20-13-7-4-8-14-20/h3-15,17H,2,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of IK channel (unknown origin)				Bioorg Med Chem Lett 23: 706-10 (2013) Article DOI: 10.1016/j.bmcl.2012.11.098 BindingDB Entry DOI: 10.7270/Q2H133BG
					More data for this Ligand-Target Pair