BDBM50425107 CHEMBL2312930
SMILES: O=P(NCc1cccnc1-c1cccc(c1)C#N)(c1ccccc1)c1ccccc1
InChI Key: InChIKey=NDJUXDNSHSEHEC-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50425107 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Voltage-gated potassium channel subunit Kv1.5
(Homo sapiens (Human)) | BDBM50425107
(CHEMBL2312930)Show SMILES O=P(NCc1cccnc1-c1cccc(c1)C#N)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H20N3OP/c26-18-20-9-7-10-21(17-20)25-22(11-8-16-27-25)19-28-30(29,23-12-3-1-4-13-23)24-14-5-2-6-15-24/h1-17H,19H2,(H,28,29) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 540 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of human Kv1.5 channel expressed in CHO cells by high throughput planar patch clamp assay |
Bioorg Med Chem Lett 23: 706-10 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.098
BindingDB Entry DOI: 10.7270/Q2H133BG |
More data for this
Ligand-Target Pair | |
Intermediate conductance calcium-activated potassium channel protein 4
(Homo sapiens (Human)) | BDBM50425107
(CHEMBL2312930)Show SMILES O=P(NCc1cccnc1-c1cccc(c1)C#N)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C25H20N3OP/c26-18-20-9-7-10-21(17-20)25-22(11-8-16-27-25)19-28-30(29,23-12-3-1-4-13-23)24-14-5-2-6-15-24/h1-17H,19H2,(H,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of IK channel (unknown origin) |
Bioorg Med Chem Lett 23: 706-10 (2013)
Article DOI: 10.1016/j.bmcl.2012.11.098
BindingDB Entry DOI: 10.7270/Q2H133BG |
More data for this
Ligand-Target Pair | |
Search and Browse
