BDBM50425173 CHEMBL2313558

SMILES: C(N1CCCCC1)c1cc2cc(Oc3nc4ccccc4s3)ccc2o1

InChI Key: InChIKey=JHJJCVVKKWGKRN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50425173   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leukotriene A4 hydrolase (Homo sapiens (Human))	BDBM50425173 (CHEMBL2313558) Show SMILES C(N1CCCCC1)c1cc2cc(Oc3nc4ccccc4s3)ccc2o1 Show InChI InChI=1S/C21H20N2O2S/c1-4-10-23(11-5-1)14-17-13-15-12-16(8-9-19(15)24-17)25-21-22-18-6-2-3-7-20(18)26-21/h2-3,6-9,12-13H,1,4-5,10-11,14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research& Development, LLC Curated by ChEMBL					Assay Description Inhibition of recombinant human LTA4H expressed in Sf9 cells using LTA4 as substrate incubated for 10 mins prior to substrate addition measured after...				Bioorg Med Chem Lett 23: 811-5 (2013) Article DOI: 10.1016/j.bmcl.2012.11.074 BindingDB Entry DOI: 10.7270/Q27H1KW1
					More data for this Ligand-Target Pair