BDBM50425397 CHEMBL2312271

SMILES: Cc1cc(NC(=O)CC(O)=O)c2CCCc2c1Oc1ccc(O)c(CCc2cccc(Cl)c2)c1

InChI Key: InChIKey=MLMFTGYMTZJDLY-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425397   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50425397 (CHEMBL2312271) Show SMILES Cc1cc(NC(=O)CC(O)=O)c2CCCc2c1Oc1ccc(O)c(CCc2cccc(Cl)c2)c1 Show InChI InChI=1S/C27H26ClNO5/c1-16-12-23(29-25(31)15-26(32)33)21-6-3-7-22(21)27(16)34-20-10-11-24(30)18(14-20)9-8-17-4-2-5-19(28)13-17/h2,4-5,10-14,30H,3,6-9,15H2,1H3,(H,29,31)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-T3 from human TRbeta expressed in insect cells after 16 to 48 hrs by gamma-counting				Bioorg Med Chem 21: 592-607 (2013) Article DOI: 10.1016/j.bmc.2012.12.002 BindingDB Entry DOI: 10.7270/Q2JS9RRW
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50425397 (CHEMBL2312271) Show SMILES Cc1cc(NC(=O)CC(O)=O)c2CCCc2c1Oc1ccc(O)c(CCc2cccc(Cl)c2)c1 Show InChI InChI=1S/C27H26ClNO5/c1-16-12-23(29-25(31)15-26(32)33)21-6-3-7-22(21)27(16)34-20-10-11-24(30)18(14-20)9-8-17-4-2-5-19(28)13-17/h2,4-5,10-14,30H,3,6-9,15H2,1H3,(H,29,31)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-T3 from human TRalpha expressed in insect cells after 16 to 48 hrs by gamma-counting				Bioorg Med Chem 21: 592-607 (2013) Article DOI: 10.1016/j.bmc.2012.12.002 BindingDB Entry DOI: 10.7270/Q2JS9RRW
					More data for this Ligand-Target Pair