BDBM50425400 CHEMBL2312268

SMILES: Cc1cc(NC(=O)CC(O)=O)c2CCCc2c1Oc1ccc(O)c(CCc2ccc(F)cc2F)c1

InChI Key: InChIKey=NDQVMFFAGUMNGI-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50425400   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Thyroid hormone receptor beta (Homo sapiens (Human))	BDBM50425400 (CHEMBL2312268) Show SMILES Cc1cc(NC(=O)CC(O)=O)c2CCCc2c1Oc1ccc(O)c(CCc2ccc(F)cc2F)c1 Show InChI InChI=1S/C27H25F2NO5/c1-15-11-23(30-25(32)14-26(33)34)20-3-2-4-21(20)27(15)35-19-9-10-24(31)17(12-19)6-5-16-7-8-18(28)13-22(16)29/h7-13,31H,2-6,14H2,1H3,(H,30,32)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-T3 from human TRbeta expressed in insect cells after 16 to 48 hrs by gamma-counting				Bioorg Med Chem 21: 592-607 (2013) Article DOI: 10.1016/j.bmc.2012.12.002 BindingDB Entry DOI: 10.7270/Q2JS9RRW
					More data for this Ligand-Target Pair
Thyroid hormone receptor alpha (Homo sapiens (Human))	BDBM50425400 (CHEMBL2312268) Show SMILES Cc1cc(NC(=O)CC(O)=O)c2CCCc2c1Oc1ccc(O)c(CCc2ccc(F)cc2F)c1 Show InChI InChI=1S/C27H25F2NO5/c1-15-11-23(30-25(32)14-26(33)34)20-3-2-4-21(20)27(15)35-19-9-10-24(31)17(12-19)6-5-16-7-8-18(28)13-22(16)29/h7-13,31H,2-6,14H2,1H3,(H,30,32)(H,33,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	201	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Kissei Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-T3 from human TRalpha expressed in insect cells after 16 to 48 hrs by gamma-counting				Bioorg Med Chem 21: 592-607 (2013) Article DOI: 10.1016/j.bmc.2012.12.002 BindingDB Entry DOI: 10.7270/Q2JS9RRW
					More data for this Ligand-Target Pair