BDBM50425828 CHEMBL2312307

SMILES: O=C(NCCCN1CCCC1=O)c1cnc(NCCc2ccccn2)nc1Nc1ccccc1

InChI Key: InChIKey=ZEXIHRLTNITJNX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50425828   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50425828 (CHEMBL2312307) Show SMILES O=C(NCCCN1CCCC1=O)c1cnc(NCCc2ccccn2)nc1Nc1ccccc1 Show InChI InChI=1S/C25H29N7O2/c33-22-11-6-16-32(22)17-7-14-27-24(34)21-18-29-25(28-15-12-19-8-4-5-13-26-19)31-23(21)30-20-9-2-1-3-10-20/h1-5,8-10,13,18H,6-7,11-12,14-17H2,(H,27,34)(H2,28,29,30,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISA				Bioorg Med Chem Lett 23: 1046-50 (2013) Article DOI: 10.1016/j.bmcl.2012.12.013 BindingDB Entry DOI: 10.7270/Q26D5V9W
					More data for this Ligand-Target Pair