BDBM50425847 CHEMBL2312315

SMILES: Clc1cccc(Cl)c1CCNc1ncc(C(=O)NCCCN2CCCC2=O)c(NC2CCCC2)n1

InChI Key: InChIKey=MZAPQKQYFWUBLS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50425847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50425847 (CHEMBL2312315) Show SMILES Clc1cccc(Cl)c1CCNc1ncc(C(=O)NCCCN2CCCC2=O)c(NC2CCCC2)n1 Show InChI InChI=1S/C25H32Cl2N6O2/c26-20-8-3-9-21(27)18(20)11-13-29-25-30-16-19(23(32-25)31-17-6-1-2-7-17)24(35)28-12-5-15-33-14-4-10-22(33)34/h3,8-9,16-17H,1-2,4-7,10-15H2,(H,28,35)(H2,29,30,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of Sky (unknown origin) in presence of 60 uM ATP by ELISA				Bioorg Med Chem Lett 23: 1046-50 (2013) Article DOI: 10.1016/j.bmcl.2012.12.013 BindingDB Entry DOI: 10.7270/Q26D5V9W
					More data for this Ligand-Target Pair