BDBM50425868 CHEMBL2312655
SMILES: O[C@@H]1COC[C@H]1Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1-c1cccnc1
InChI Key: InChIKey=ALEHKALCLNFZHW-IAGOWNOFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50425868 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human)) | BDBM50425868
(CHEMBL2312655)Show SMILES O[C@@H]1COC[C@H]1Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1-c1cccnc1 |r| Show InChI InChI=1S/C19H17Cl2N5O2/c20-12-4-13(21)6-14(5-12)24-19-23-8-15(11-2-1-3-22-7-11)18(26-19)25-16-9-28-10-17(16)27/h1-8,16-17,27H,9-10H2,(H2,23,24,25,26)/t16-,17-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 44 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATP |
Bioorg Med Chem Lett 23: 1051-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.028
BindingDB Entry DOI: 10.7270/Q2XW4M38 |
More data for this
Ligand-Target Pair | |
P-selectin/P-selectin glycoprotein ligand 1
(Homo sapiens (Human)) | BDBM50425868
(CHEMBL2312655)Show SMILES O[C@@H]1COC[C@H]1Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1-c1cccnc1 |r| Show InChI InChI=1S/C19H17Cl2N5O2/c20-12-4-13(21)6-14(5-12)24-19-23-8-15(11-2-1-3-22-7-11)18(26-19)25-16-9-28-10-17(16)27/h1-8,16-17,27H,9-10H2,(H2,23,24,25,26)/t16-,17-/m1/s1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of P-selectin aggregation in platelet surface (unknown origin) |
Bioorg Med Chem Lett 23: 1051-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.028
BindingDB Entry DOI: 10.7270/Q2XW4M38 |
More data for this
Ligand-Target Pair | |
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