Found 2 hits for monomerid = 50425873 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Tyrosine-protein kinase receptor TYRO3
(Homo sapiens (Human)) | BDBM50425873
(CHEMBL2312648)Show SMILES CN(C)C1CCC(CC1)Nc1nc(NCc2cc(Cl)ccc2Cl)ncc1C(=O)NC1CCN(C)CC1 |(25.27,-50.31,;26.81,-50.32,;27.57,-51.65,;27.59,-48.99,;26.83,-47.65,;27.6,-46.32,;29.13,-46.34,;29.91,-47.66,;29.13,-49,;29.91,-45.01,;29.14,-43.67,;27.6,-43.67,;26.84,-42.33,;25.3,-42.33,;24.53,-43.66,;22.99,-43.66,;22.22,-44.99,;20.69,-44.99,;19.92,-46.32,;19.91,-43.65,;20.69,-42.32,;22.22,-42.32,;23,-40.99,;27.6,-41,;29.14,-41,;29.91,-42.34,;31.45,-42.34,;32.22,-43.67,;32.23,-41.01,;33.77,-41.01,;34.53,-42.34,;36.06,-42.35,;36.84,-41.02,;38.38,-41.03,;36.07,-39.68,;34.53,-39.67,)| Show InChI InChI=1S/C26H37Cl2N7O/c1-34(2)21-7-5-19(6-8-21)31-24-22(25(36)32-20-10-12-35(3)13-11-20)16-30-26(33-24)29-15-17-14-18(27)4-9-23(17)28/h4,9,14,16,19-21H,5-8,10-13,15H2,1-3H3,(H,32,36)(H2,29,30,31,33) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of Sky (unknown origin) by ELISA kinase assay in presence of 60 uM ATP |
Bioorg Med Chem Lett 23: 1051-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.028
BindingDB Entry DOI: 10.7270/Q2XW4M38 |
More data for this
Ligand-Target Pair | |
P-selectin/P-selectin glycoprotein ligand 1
(Homo sapiens (Human)) | BDBM50425873
(CHEMBL2312648)Show SMILES CN(C)C1CCC(CC1)Nc1nc(NCc2cc(Cl)ccc2Cl)ncc1C(=O)NC1CCN(C)CC1 |(25.27,-50.31,;26.81,-50.32,;27.57,-51.65,;27.59,-48.99,;26.83,-47.65,;27.6,-46.32,;29.13,-46.34,;29.91,-47.66,;29.13,-49,;29.91,-45.01,;29.14,-43.67,;27.6,-43.67,;26.84,-42.33,;25.3,-42.33,;24.53,-43.66,;22.99,-43.66,;22.22,-44.99,;20.69,-44.99,;19.92,-46.32,;19.91,-43.65,;20.69,-42.32,;22.22,-42.32,;23,-40.99,;27.6,-41,;29.14,-41,;29.91,-42.34,;31.45,-42.34,;32.22,-43.67,;32.23,-41.01,;33.77,-41.01,;34.53,-42.34,;36.06,-42.35,;36.84,-41.02,;38.38,-41.03,;36.07,-39.68,;34.53,-39.67,)| Show InChI InChI=1S/C26H37Cl2N7O/c1-34(2)21-7-5-19(6-8-21)31-24-22(25(36)32-20-10-12-35(3)13-11-20)16-30-26(33-24)29-15-17-14-18(27)4-9-23(17)28/h4,9,14,16,19-21H,5-8,10-13,15H2,1-3H3,(H,32,36)(H2,29,30,31,33) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description
Inhibition of P-selectin aggregation in platelet surface (unknown origin) |
Bioorg Med Chem Lett 23: 1051-5 (2013)
Article DOI: 10.1016/j.bmcl.2012.12.028
BindingDB Entry DOI: 10.7270/Q2XW4M38 |
More data for this
Ligand-Target Pair | |
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