Found 4 hits for monomerid = 50426303 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
cAMP-specific 3',5'-cyclic phosphodiesterase 4A
(Homo sapiens (Human)) | BDBM50426303
(CHEMBL2312697)Show SMILES [#6]-[#6@H]-1-[#6](=O)-[#7]-c2ccc(cc-12)-c1csc(\[#7]=[#6](\[#7])-[#7])n1 |r| Show InChI InChI=1S/C13H13N5OS/c1-6-8-4-7(2-3-9(8)16-11(6)19)10-5-20-13(17-10)18-12(14)15/h2-6H,1H3,(H,16,19)(H4,14,15,17,18)/t6-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.15E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network
Curated by ChEMBL
| Assay Description
Inhibition of PAD4 (unknown origin) at 37 degC |
J Med Chem 56: 1715-22 (2013)
Article DOI: 10.1021/jm301755q
BindingDB Entry DOI: 10.7270/Q2ZS2XTX |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A
(Homo sapiens (Human)) | BDBM50426303
(CHEMBL2312697)Show SMILES [#6]-[#6@H]-1-[#6](=O)-[#7]-c2ccc(cc-12)-c1csc(\[#7]=[#6](\[#7])-[#7])n1 |r| Show InChI InChI=1S/C13H13N5OS/c1-6-8-4-7(2-3-9(8)16-11(6)19)10-5-20-13(17-10)18-12(14)15/h2-6H,1H3,(H,16,19)(H4,14,15,17,18)/t6-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 2.31E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network
Curated by ChEMBL
| Assay Description
Inhibition of PAD4 (unknown origin) at 52 degC |
J Med Chem 56: 1715-22 (2013)
Article DOI: 10.1021/jm301755q
BindingDB Entry DOI: 10.7270/Q2ZS2XTX |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A
(Homo sapiens (Human)) | BDBM50426303
(CHEMBL2312697)Show SMILES [#6]-[#6@H]-1-[#6](=O)-[#7]-c2ccc(cc-12)-c1csc(\[#7]=[#6](\[#7])-[#7])n1 |r| Show InChI InChI=1S/C13H13N5OS/c1-6-8-4-7(2-3-9(8)16-11(6)19)10-5-20-13(17-10)18-12(14)15/h2-6H,1H3,(H,16,19)(H4,14,15,17,18)/t6-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.32E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network
Curated by ChEMBL
| Assay Description
Inhibition of PAD4 (unknown origin) at 37 degC |
J Med Chem 56: 1715-22 (2013)
Article DOI: 10.1021/jm301755q
BindingDB Entry DOI: 10.7270/Q2ZS2XTX |
More data for this
Ligand-Target Pair | |
cAMP-specific 3',5'-cyclic phosphodiesterase 4A
(Homo sapiens (Human)) | BDBM50426303
(CHEMBL2312697)Show SMILES [#6]-[#6@H]-1-[#6](=O)-[#7]-c2ccc(cc-12)-c1csc(\[#7]=[#6](\[#7])-[#7])n1 |r| Show InChI InChI=1S/C13H13N5OS/c1-6-8-4-7(2-3-9(8)16-11(6)19)10-5-20-13(17-10)18-12(14)15/h2-6H,1H3,(H,16,19)(H4,14,15,17,18)/t6-/m1/s1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2.65E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
University Health Network
Curated by ChEMBL
| Assay Description
Inhibition of PAD4 (unknown origin) at 52 degC |
J Med Chem 56: 1715-22 (2013)
Article DOI: 10.1021/jm301755q
BindingDB Entry DOI: 10.7270/Q2ZS2XTX |
More data for this
Ligand-Target Pair | |
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