BDBM50426432 CHEMBL2322361

SMILES: Cc1ccc(cc1-c1nc2cc(ncc2[nH]1)N1CCC1)C(=O)N1CCC(CC1)c1ccc(cc1)C#N

InChI Key: InChIKey=ZQWHAXATAXETST-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50426432   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty acid synthase (Homo sapiens (Human))	BDBM50426432 (CHEMBL2322361) Show SMILES Cc1ccc(cc1-c1nc2cc(ncc2[nH]1)N1CCC1)C(=O)N1CCC(CC1)c1ccc(cc1)C#N Show InChI InChI=1S/C29H28N6O/c1-19-3-6-23(29(36)35-13-9-22(10-14-35)21-7-4-20(17-30)5-8-21)15-24(19)28-32-25-16-27(34-11-2-12-34)31-18-26(25)33-28/h3-8,15-16,18,22H,2,9-14H2,1H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
3-V Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of human FASN assessed as release of co-enzyme A				ACS Med Chem Lett 4: 113-7 (2013) Article DOI: 10.1021/ml300335r BindingDB Entry DOI: 10.7270/Q2P84D76
					More data for this Ligand-Target Pair
Fatty acid synthase (Rattus norvegicus)	BDBM50426432 (CHEMBL2322361) Show SMILES Cc1ccc(cc1-c1nc2cc(ncc2[nH]1)N1CCC1)C(=O)N1CCC(CC1)c1ccc(cc1)C#N Show InChI InChI=1S/C29H28N6O/c1-19-3-6-23(29(36)35-13-9-22(10-14-35)21-7-4-20(17-30)5-8-21)15-24(19)28-32-25-16-27(34-11-2-12-34)31-18-26(25)33-28/h3-8,15-16,18,22H,2,9-14H2,1H3,(H,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	397	n/a	n/a	n/a	n/a	n/a	n/a
3-V Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of rat FASN assessed as release of co-enzyme A				ACS Med Chem Lett 4: 113-7 (2013) Article DOI: 10.1021/ml300335r BindingDB Entry DOI: 10.7270/Q2P84D76
					More data for this Ligand-Target Pair