BDBM50426576 CHEMBL2324346

SMILES: Cc1ccn(n1)-c1nc(Nc2ccc(F)cc2)c2ncn(C)c2n1

InChI Key: InChIKey=FHAJWQLFSSJBAK-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50426576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Small conductance calcium-activated potassium channel protein 3 (KCa2.3) (Homo sapiens (Human))	BDBM50426576 (CHEMBL2324346) Show SMILES Cc1ccn(n1)-c1nc(Nc2ccc(F)cc2)c2ncn(C)c2n1 Show InChI InChI=1S/C16H14FN7/c1-10-7-8-24(22-10)16-20-14(13-15(21-16)23(2)9-18-13)19-12-5-3-11(17)4-6-12/h3-9H,1-2H3,(H,19,20,21)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of human Kca 2.3 expressed in HEK293 cells by patch clamp technique				J Med Chem 56: 593-624 (2013) Article DOI: 10.1021/jm3011433 BindingDB Entry DOI: 10.7270/Q23B61GZ
					More data for this Ligand-Target Pair