BDBM50426621 CHEMBL2325935

SMILES: CN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2ccc(cc12)-c1nnn(C)n1

InChI Key: InChIKey=LSOSTOVOMJGNDT-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50426621   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cerebral cortex alpha adrenergic receptor (CALF)	BDBM50426621 (CHEMBL2325935) Show SMILES CN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2ccc(cc12)-c1nnn(C)n1 Show InChI InChI=1S/C22H23FN6/c1-27-11-9-15(10-12-27)20-14-29(18-6-4-17(23)5-7-18)21-8-3-16(13-19(20)21)22-24-26-28(2)25-22/h3-8,13-15H,9-12H2,1-2H3	KEGG GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosine from bovine alpha1A adrenoceptor expressed in BHK cells after 20 mins by scintillation counting analysis				Bioorg Med Chem 21: 196-204 (2012) Article DOI: 10.1016/j.bmc.2012.10.049 BindingDB Entry DOI: 10.7270/Q2K938VN
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50426621 (CHEMBL2325935) Show SMILES CN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2ccc(cc12)-c1nnn(C)n1 Show InChI InChI=1S/C22H23FN6/c1-27-11-9-15(10-12-27)20-14-29(18-6-4-17(23)5-7-18)21-8-3-16(13-19(20)21)22-24-26-28(2)25-22/h3-8,13-15H,9-12H2,1-2H3	PDB Reactome pathway KEGG DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2 receptor expressed in CHO cells after 30 mins by scintillation counting analysis				Bioorg Med Chem 21: 196-204 (2012) Article DOI: 10.1016/j.bmc.2012.10.049 BindingDB Entry DOI: 10.7270/Q2K938VN
					More data for this Ligand-Target Pair