BDBM50426630 CHEMBL2325926
SMILES: CN1CCC(CC1)c1cn(-c2ccc(F)cc2)c2ccc(cc12)-c1ccnn1C
InChI Key: InChIKey=WRURBHLNYRDTFF-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cerebral cortex alpha adrenergic receptor (CALF) | BDBM50426630 (CHEMBL2325926) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S Curated by ChEMBL | Assay Description Displacement of [3H]prazosine from bovine alpha1A adrenoceptor expressed in BHK cells after 20 mins by scintillation counting analysis | Bioorg Med Chem 21: 196-204 (2012) Article DOI: 10.1016/j.bmc.2012.10.049 BindingDB Entry DOI: 10.7270/Q2K938VN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Homo sapiens (Human)) | BDBM50426630 (CHEMBL2325926) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
H. Lundbeck A/S Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from human dopamine D2 receptor expressed in CHO cells after 30 mins by scintillation counting analysis | Bioorg Med Chem 21: 196-204 (2012) Article DOI: 10.1016/j.bmc.2012.10.049 BindingDB Entry DOI: 10.7270/Q2K938VN | |||||||||||
More data for this Ligand-Target Pair |