null
SMILES: COc1ccc(cc1)-c1cn(nn1)-c1ccc2OS(=O)(=O)C=Cc2c1
InChI Key: InChIKey=MYGNMPNPSLIBHM-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 9 (Homo sapiens (Human)) | BDBM50426696 (CHEMBL2326520) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of human recombinant transmembrane CA9 catalytic domain after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 12 (Homo sapiens (Human)) | BDBM50426696 (CHEMBL2326520) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of human recombinant transmembrane CA12 catalytic domain after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 1 (Homo sapiens (Human)) | BDBM50426696 (CHEMBL2326520) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 8.93E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA1 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 2 (Homo sapiens (Human)) | BDBM50426696 (CHEMBL2326520) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 9.35E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Latvian Association of Human Genetics Curated by ChEMBL | Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method | J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW | |||||||||||
More data for this Ligand-Target Pair |