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SMILES: C[Si](C)(C)c1cn(nn1)-c1ccc2OS(=O)(=O)C=Cc2c1

InChI Key: InChIKey=AZIZDXJGHAGKNH-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50426700   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50426700 (CHEMBL2326516) Show SMILES C[Si](C)(C)c1cn(nn1)-c1ccc2OS(=O)(=O)C=Cc2c1 |c:18| Show InChI InChI=1S/C13H15N3O3SSi/c1-21(2,3)13-9-16(15-14-13)11-4-5-12-10(8-11)6-7-20(17,18)19-12/h4-9H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane CA12 catalytic domain after 6 hrs by stopped-flow CO2 hydration method				J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50426700 (CHEMBL2326516) Show SMILES C[Si](C)(C)c1cn(nn1)-c1ccc2OS(=O)(=O)C=Cc2c1 |c:18| Show InChI InChI=1S/C13H15N3O3SSi/c1-21(2,3)13-9-16(15-14-13)11-4-5-12-10(8-11)6-7-20(17,18)19-12/h4-9H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of human recombinant transmembrane CA9 catalytic domain after 6 hrs by stopped-flow CO2 hydration method				J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50426700 (CHEMBL2326516) Show SMILES C[Si](C)(C)c1cn(nn1)-c1ccc2OS(=O)(=O)C=Cc2c1 |c:18| Show InChI InChI=1S/C13H15N3O3SSi/c1-21(2,3)13-9-16(15-14-13)11-4-5-12-10(8-11)6-7-20(17,18)19-12/h4-9H,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	6.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of full length human recombinant CA1 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method				J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50426700 (CHEMBL2326516) Show SMILES C[Si](C)(C)c1cn(nn1)-c1ccc2OS(=O)(=O)C=Cc2c1 |c:18| Show InChI InChI=1S/C13H15N3O3SSi/c1-21(2,3)13-9-16(15-14-13)11-4-5-12-10(8-11)6-7-20(17,18)19-12/h4-9H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Latvian Association of Human Genetics Curated by ChEMBL					Assay Description Inhibition of full length human recombinant CA2 cytosolic isoform after 6 hrs by stopped-flow CO2 hydration method				J Med Chem 56: 293-300 (2013) Article DOI: 10.1021/jm301625s BindingDB Entry DOI: 10.7270/Q2XK8GVW
					More data for this Ligand-Target Pair