BDBM50427077 CHEMBL2322847

SMILES: COc1cc(ccc1Cl)N1CCN(CC1)C(=O)Cn1nc(C#N)c(Cl)c1C

InChI Key: InChIKey=DRGKPDHHIJCGIK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427077   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50427077 (CHEMBL2322847) Show SMILES COc1cc(ccc1Cl)N1CCN(CC1)C(=O)Cn1nc(C#N)c(Cl)c1C Show InChI InChI=1S/C18H19Cl2N5O2/c1-12-18(20)15(10-21)22-25(12)11-17(26)24-7-5-23(6-8-24)13-3-4-14(19)16(9-13)27-2/h3-4,9H,5-8,11H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-CCL3/MIP-1alpha from CCR1 in human THP1 cells				Bioorg Med Chem Lett 23: 1228-31 (2013) Article DOI: 10.1016/j.bmcl.2013.01.005 BindingDB Entry DOI: 10.7270/Q2NZ88Z2
					More data for this Ligand-Target Pair