BDBM50427086 CHEMBL2322867

SMILES: COc1cc(ccc1Cl)N1CCN(CC1)C(=O)Cn1nc(c(Cl)c1CO)C(F)(F)F

InChI Key: InChIKey=VKZVZRUJYXLBOI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427086   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM50427086 (CHEMBL2322867) Show SMILES COc1cc(ccc1Cl)N1CCN(CC1)C(=O)Cn1nc(c(Cl)c1CO)C(F)(F)F Show InChI InChI=1S/C18H19Cl2F3N4O3/c1-30-14-8-11(2-3-12(14)19)25-4-6-26(7-5-25)15(29)9-27-13(10-28)16(20)17(24-27)18(21,22)23/h2-3,8,28H,4-7,9-10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
ChemoCentryx, Inc. Curated by ChEMBL					Assay Description Displacement of [125I]-CCL3/MIP-1alpha from CCR1 in human THP1 cells				Bioorg Med Chem Lett 23: 1228-31 (2013) Article DOI: 10.1016/j.bmcl.2013.01.005 BindingDB Entry DOI: 10.7270/Q2NZ88Z2
					More data for this Ligand-Target Pair