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SMILES: COc1ccc(cc1)C(CC(F)(F)CN)(c1ccccc1)c1ccc(C)cc1

InChI Key: InChIKey=JWWYDJQOFFYDIA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427292   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Kinesin-like protein KIF11


(Homo sapiens (Human))		BDBM50427292
PNG
(CHEMBL2325427)
Show SMILES COc1ccc(cc1)C(CC(F)(F)CN)(c1ccccc1)c1ccc(C)cc1
Show InChI InChI=1S/C24H25F2NO/c1-18-8-10-20(11-9-18)24(16-23(25,26)17-27,19-6-4-3-5-7-19)21-12-14-22(28-2)15-13-21/h3-15H,16-17,27H2,1-2H3
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Article
PubMed
 88n/an/an/an/an/an/an/an/a



The Beatson Institute for Cancer Research

Curated by ChEMBL


Assay Description
Inhibition of human N-terminal His6-tagged Eg5 (1 to 368 amino acid residues) motor domain basal ATPase activity expressed in Escherichia coli BL21 (...

J Med Chem 56: 1878-93 (2013)


Article DOI: 10.1021/jm3014597
BindingDB Entry DOI: 10.7270/Q20866NN
More data for this
Ligand-Target Pair