BDBM50427515 CHEMBL2322248

SMILES: Cc1c(CCC(=O)Nc2ccc(NS(C)(=O)=O)cc2)c(=O)oc2c(C)c3oc4CCCCc4c3cc12

InChI Key: InChIKey=NJUKMLYHBUWYKR-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nuclear factor NF-kappa-B (NF-kB) (Homo sapiens (Human))	BDBM50427515 (CHEMBL2322248) Show SMILES Cc1c(CCC(=O)Nc2ccc(NS(C)(=O)=O)cc2)c(=O)oc2c(C)c3oc4CCCCc4c3cc12 Show InChI InChI=1S/C27H28N2O6S/c1-15-19(12-13-24(30)28-17-8-10-18(11-9-17)29-36(3,32)33)27(31)35-25-16(2)26-22(14-21(15)25)20-6-4-5-7-23(20)34-26/h8-11,14,29H,4-7,12-13H2,1-3H3,(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.00E+6	n/a	n/a	n/a	n/a
Universit£ degli Studi di Padova Curated by ChEMBL					Assay Description Inhibition of human NF-kappaB p50/DNA interaction using 32P-labeled oligonucleotides as substrate preincubated for 20 mins before substrate addition ...				J Med Chem 56: 1830-42 (2013) Article DOI: 10.1021/jm3009647 BindingDB Entry DOI: 10.7270/Q2TH8P10
					More data for this Ligand-Target Pair