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BDBM50427724 CHEMBL2324223

SMILES: CNC(=O)\C=C1\COc2cc(OS(=O)(=O)CCC(F)(F)F)ccc12

InChI Key: InChIKey=BSUGXTFBDJHTEX-TWGQIWQCSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427724   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine oxidase


(Rattus norvegicus (rat))
BDBM50427724
PNG
(CHEMBL2324223)
Show SMILES CNC(=O)\C=C1\COc2cc(OS(=O)(=O)CCC(F)(F)F)ccc12
Show InChI InChI=1S/C14H14F3NO5S/c1-18-13(19)6-9-8-22-12-7-10(2-3-11(9)12)23-24(20,21)5-4-14(15,16)17/h2-3,6-7H,4-5,8H2,1H3,(H,18,19)/b9-6-
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.10n/an/an/an/an/an/a



Universit£ degli Studi di Bari"Aldo Moro"

Curated by ChEMBL


Assay Description
Inhibition of MAO-A in Sprague-Dawley rat brain mitochondrial suspension using kynuramine as substrate incubated for 5 mins prior to substrate additi...


J Med Chem 56: 2651-64 (2013)


Article DOI: 10.1021/jm4000769
BindingDB Entry DOI: 10.7270/Q28K7BD4
More data for this
Ligand-Target Pair