BDBM50427754 CHEMBL2325166

SMILES: O=C(NCCCN1CCOCC1)Nc1ccc2nnsc2c1

InChI Key: InChIKey=CFHVOBXPZOWQMW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427754   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine methyltransferase 3 (PRMT3) (Homo sapiens (Human))	BDBM50427754 (CHEMBL2325166) Show SMILES O=C(NCCCN1CCOCC1)Nc1ccc2nnsc2c1 Show InChI InChI=1S/C14H19N5O2S/c20-14(15-4-1-5-19-6-8-21-9-7-19)16-11-2-3-12-13(10-11)22-18-17-12/h2-3,10H,1,4-9H2,(H2,15,16,20)	PDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...				J Med Chem 56: 2110-24 (2013) Article DOI: 10.1021/jm3018332 BindingDB Entry DOI: 10.7270/Q2W95BHJ
					More data for this Ligand-Target Pair