BDBM50427761 CHEMBL2325448

SMILES: O=c1c(NCCC2CCCCC2)c(Nc2ccc3nnsc3c2)c1=O

InChI Key: InChIKey=LUBLRFOOZPRUAW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine N-methyltransferase 3 (Homo sapiens (Human))	BDBM50427761 (CHEMBL2325448) Show SMILES O=c1c(NCCC2CCCCC2)c(Nc2ccc3nnsc3c2)c1=O Show InChI InChI=1S/C18H20N4O2S/c23-17-15(19-9-8-11-4-2-1-3-5-11)16(18(17)24)20-12-6-7-13-14(10-12)25-22-21-13/h6-7,10-11,19-20H,1-5,8-9H2	PDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...				J Med Chem 56: 2110-24 (2013) Article DOI: 10.1021/jm3018332 BindingDB Entry DOI: 10.7270/Q2W95BHJ
					More data for this Ligand-Target Pair