BDBM50427770 CHEMBL2325185

SMILES: O=C(NCCC1CCNCC1)Nc1ccc2nnsc2c1

InChI Key: InChIKey=RFXWGGMEQRVEMR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427770   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine methyltransferase 3 (PRMT3) (Homo sapiens (Human))	BDBM50427770 (CHEMBL2325185) Show SMILES O=C(NCCC1CCNCC1)Nc1ccc2nnsc2c1 Show InChI InChI=1S/C14H19N5OS/c20-14(16-8-5-10-3-6-15-7-4-10)17-11-1-2-12-13(9-11)21-19-18-12/h1-2,9-10,15H,3-8H2,(H2,16,17,20)	PDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...				J Med Chem 56: 2110-24 (2013) Article DOI: 10.1021/jm3018332 BindingDB Entry DOI: 10.7270/Q2W95BHJ
					More data for this Ligand-Target Pair