BDBM50427774 CHEMBL2325181

SMILES: Fc1ccc(CNC(=O)Nc2ccc3nnsc3c2)cc1

InChI Key: InChIKey=MXXVLPJIRFWSRP-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50427774   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein arginine methyltransferase 3 (PRMT3) (Homo sapiens (Human))	BDBM50427774 (CHEMBL2325181) Show SMILES Fc1ccc(CNC(=O)Nc2ccc3nnsc3c2)cc1 Show InChI InChI=1S/C14H11FN4OS/c15-10-3-1-9(2-4-10)8-16-14(20)17-11-5-6-12-13(7-11)21-19-18-12/h1-7H,8H2,(H2,16,17,20)	PDB B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill Curated by ChEMBL					Assay Description Inhibition of PRMT3 (unknown origin) using histone H4 (1 to 24) as substrate after 1 hr by scintillation proximity assay in presence of [3H]-S-adenos...				J Med Chem 56: 2110-24 (2013) Article DOI: 10.1021/jm3018332 BindingDB Entry DOI: 10.7270/Q2W95BHJ
					More data for this Ligand-Target Pair