null

SMILES: Fc1cccc(c1)N1CNC(=O)C11CCN(CCNC(=O)c2ccc(Br)cc2)CC1

InChI Key: InChIKey=PYFQAQXMZAWSDV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50427806   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase D1 (Homo sapiens (Human))	BDBM50427806 (CHEMBL2325484) Show SMILES Fc1cccc(c1)N1CNC(=O)C11CCN(CCNC(=O)c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C22H24BrFN4O2/c23-17-6-4-16(5-7-17)20(29)25-10-13-27-11-8-22(9-12-27)21(30)26-15-28(22)19-3-1-2-18(24)14-19/h1-7,14H,8-13,15H2,(H,25,29)(H,26,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.54E+3	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of PLD1 in human Calu-1 cells assessed as deuterated 1-butanol incorporation pretreated for 5 mins prior to substrate addition measured af...				J Med Chem 56: 2695-9 (2013) Article DOI: 10.1021/jm301782e BindingDB Entry DOI: 10.7270/Q2RJ4KT8
					More data for this Ligand-Target Pair
Phospholipase D2 (Homo sapiens (Human))	BDBM50427806 (CHEMBL2325484) Show SMILES Fc1cccc(c1)N1CNC(=O)C11CCN(CCNC(=O)c2ccc(Br)cc2)CC1 Show InChI InChI=1S/C22H24BrFN4O2/c23-17-6-4-16(5-7-17)20(29)25-10-13-27-11-8-22(9-12-27)21(30)26-15-28(22)19-3-1-2-18(24)14-19/h1-7,14H,8-13,15H2,(H,25,29)(H,26,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of GFP-tagged PLD2 in human HEK293 cells assessed as deuterated 1-butanol incorporation pretreated for 5 mins prior to substrate addition ...				J Med Chem 56: 2695-9 (2013) Article DOI: 10.1021/jm301782e BindingDB Entry DOI: 10.7270/Q2RJ4KT8
					More data for this Ligand-Target Pair