BDBM50428068 CHEMBL2322655::Cinnabarinic acid
SMILES: Nc1c(C(O)=O)c2nc3c(cccc3oc2cc1=O)C(O)=O
InChI Key: InChIKey=FSBKJYLVDRVPTK-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human)) | BDBM50428068 (CHEMBL2322655 | Cinnabarinic acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem | Article PubMed | 326 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nottingham Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminus 6X-histidine-tagged indoleamine 2,3-dioxygenase expressed in Escherichia coli assessed as inhibition of L-... | J Med Chem 56: 3310-7 (2013) Article DOI: 10.1021/jm400049z BindingDB Entry DOI: 10.7270/Q29C6ZRX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Indoleamine 2,3-dioxygenase 1 (Homo sapiens (Human)) | BDBM50428068 (CHEMBL2322655 | Cinnabarinic acid) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 460 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Nottingham Curated by ChEMBL | Assay Description Inhibition of human recombinant N-terminus 6X-histidine-tagged indoleamine 2,3-dioxygenase expressed in Escherichia coli assessed as inhibition of L-... | J Med Chem 56: 3310-7 (2013) Article DOI: 10.1021/jm400049z BindingDB Entry DOI: 10.7270/Q29C6ZRX | |||||||||||
More data for this Ligand-Target Pair |