BDBM50428328 CHEMBL2338391

SMILES: Cc1c(NC[C@H]2CCC[C@H](O2)c2ccc(cc2)C(F)(F)F)nc(nc1C(=O)N1CCC(CC1)N[C@H]1CCOC[C@H]1F)C1CCOCC1

InChI Key: InChIKey=FFBYNQCXDQNNQT-GKQHHHCTSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50428328   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50428328 (CHEMBL2338391) Show SMILES Cc1c(NC[C@H]2CCC[C@H](O2)c2ccc(cc2)C(F)(F)F)nc(nc1C(=O)N1CCC(CC1)N[C@H]1CCOC[C@H]1F)C1CCOCC1 |r| Show InChI InChI=1S/C34H45F4N5O4/c1-21-30(33(44)43-14-9-25(10-15-43)40-28-13-18-46-20-27(28)35)41-32(23-11-16-45-17-12-23)42-31(21)39-19-26-3-2-4-29(47-26)22-5-7-24(8-6-22)34(36,37)38/h5-8,23,25-29,40H,2-4,9-20H2,1H3,(H,39,41,42)/t26-,27-,28+,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]MCP1 from CCR2 in human THP1 cell membranes after 8 hrs by scintillation counting analysis				ACS Med Chem Lett 4: 371-2 (2013) Article DOI: 10.1021/ml400055e BindingDB Entry DOI: 10.7270/Q2B859FX
					More data for this Ligand-Target Pair
C-C chemokine receptor type 5 (Homo sapiens (Human))	BDBM50428328 (CHEMBL2338391) Show SMILES Cc1c(NC[C@H]2CCC[C@H](O2)c2ccc(cc2)C(F)(F)F)nc(nc1C(=O)N1CCC(CC1)N[C@H]1CCOC[C@H]1F)C1CCOCC1 |r| Show InChI InChI=1S/C34H45F4N5O4/c1-21-30(33(44)43-14-9-25(10-15-43)40-28-13-18-46-20-27(28)35)41-32(23-11-16-45-17-12-23)42-31(21)39-19-26-3-2-4-29(47-26)22-5-7-24(8-6-22)34(36,37)38/h5-8,23,25-29,40H,2-4,9-20H2,1H3,(H,39,41,42)/t26-,27-,28+,29+/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Therachem Research Medilab (India) Pvt. Ltd. Curated by ChEMBL					Assay Description Displacement of [125I]RANTES from human CCR5 expressed in CHO cell membranes coexpressing Gal6 after 6 hrs by scintillation counting analysis				ACS Med Chem Lett 4: 371-2 (2013) Article DOI: 10.1021/ml400055e BindingDB Entry DOI: 10.7270/Q2B859FX
					More data for this Ligand-Target Pair