BDBM50428403 CHEMBL2333975

SMILES: Nc1ccc(cc1)S(=O)(=O)NCCC(F)F

InChI Key: InChIKey=XHJUWRCGUMTFCU-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50428403   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 12 (Homo sapiens (Human))	BDBM50428403 (CHEMBL2333975) Show SMILES Nc1ccc(cc1)S(=O)(=O)NCCC(F)F Show InChI InChI=1S/C9H12F2N2O2S/c10-9(11)5-6-13-16(14,15)8-3-1-7(12)2-4-8/h1-4,9,13H,5-6,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Superacide et Chimie des syst£mes£ team-Universit£ de Poitiers Curated by ChEMBL					Assay Description Inhibition of human catalytic domain of carbonic anhydrase 12 preincubated for 15 mins by CO2 hydration stopped-flow assay				Bioorg Med Chem 21: 1555-63 (2013) Article DOI: 10.1016/j.bmc.2012.05.037 BindingDB Entry DOI: 10.7270/Q25H7HM8
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Homo sapiens (Human))	BDBM50428403 (CHEMBL2333975) Show SMILES Nc1ccc(cc1)S(=O)(=O)NCCC(F)F Show InChI InChI=1S/C9H12F2N2O2S/c10-9(11)5-6-13-16(14,15)8-3-1-7(12)2-4-8/h1-4,9,13H,5-6,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Superacide et Chimie des syst£mes£ team-Universit£ de Poitiers Curated by ChEMBL					Assay Description Inhibition of human catalytic domain of carbonic anhydrase 9 preincubated for 15 mins by CO2 hydration stopped-flow assay				Bioorg Med Chem 21: 1555-63 (2013) Article DOI: 10.1016/j.bmc.2012.05.037 BindingDB Entry DOI: 10.7270/Q25H7HM8
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50428403 (CHEMBL2333975) Show SMILES Nc1ccc(cc1)S(=O)(=O)NCCC(F)F Show InChI InChI=1S/C9H12F2N2O2S/c10-9(11)5-6-13-16(14,15)8-3-1-7(12)2-4-8/h1-4,9,13H,5-6,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.22E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Superacide et Chimie des syst£mes£ team-Universit£ de Poitiers Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assay				Bioorg Med Chem 21: 1555-63 (2013) Article DOI: 10.1016/j.bmc.2012.05.037 BindingDB Entry DOI: 10.7270/Q25H7HM8
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50428403 (CHEMBL2333975) Show SMILES Nc1ccc(cc1)S(=O)(=O)NCCC(F)F Show InChI InChI=1S/C9H12F2N2O2S/c10-9(11)5-6-13-16(14,15)8-3-1-7(12)2-4-8/h1-4,9,13H,5-6,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Superacide et Chimie des syst£mes£ team-Universit£ de Poitiers Curated by ChEMBL					Assay Description Inhibition of human recombinant carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assay				Bioorg Med Chem 21: 1555-63 (2013) Article DOI: 10.1016/j.bmc.2012.05.037 BindingDB Entry DOI: 10.7270/Q25H7HM8
					More data for this Ligand-Target Pair