BDBM50428951 CHEMBL2333179

SMILES: C[C@@H](NC(=O)CCCCCCCCCCCN(C)C)[C@@H](O)c1ccccc1

InChI Key: InChIKey=BHASEPQTXPWRLY-NFBKMPQASA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50428951   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neutral ceramidase (Homo sapiens (Human))	BDBM50428951 (CHEMBL2333179) Show SMILES C[C@@H](NC(=O)CCCCCCCCCCCN(C)C)[C@@H](O)c1ccccc1 |r| Show InChI InChI=1S/C23H40N2O2/c1-20(23(27)21-16-12-11-13-17-21)24-22(26)18-14-9-7-5-4-6-8-10-15-19-25(2)3/h11-13,16-17,20,23,27H,4-10,14-15,18-19H2,1-3H3,(H,24,26)/t20-,23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Humboldt Universit£t zu Berlin Curated by ChEMBL					Assay Description Inhibition of human recombinant neutral ceramidase using Acyl-NBD-C12-cer as substrate after 2 hrs by fluorescence assay				Bioorg Med Chem 21: 874-82 (2013) Article DOI: 10.1016/j.bmc.2012.12.014 BindingDB Entry DOI: 10.7270/Q29Z9673
					More data for this Ligand-Target Pair