BDBM50429482 CHEMBL2332869

SMILES: FC(F)(F)Oc1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1

InChI Key: InChIKey=GBJNDWYKXHMGPB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429482   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Danio rerio)	BDBM50429482 (CHEMBL2332869) Show SMILES FC(F)(F)Oc1cccc(NC(=O)Nc2ccc(Oc3ncnc4n[nH]cc34)cc2)c1 Show InChI InChI=1S/C19H13F3N6O3/c20-19(21,22)31-14-3-1-2-12(8-14)27-18(29)26-11-4-6-13(7-5-11)30-17-15-9-25-28-16(15)23-10-24-17/h1-10H,(H2,26,27,29)(H,23,24,25,28)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...				J Med Chem 56: 1641-55 (2013) Article DOI: 10.1021/jm301537p BindingDB Entry DOI: 10.7270/Q29S1SC5
					More data for this Ligand-Target Pair