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SMILES: Brc1ccc(cc1)C(=O)Nc1ccc(Oc2ncnc3n[nH]cc23)cc1

InChI Key: InChIKey=ZMHUAURSSPWVGN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429493   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Danio rerio)		BDBM50429493
PNG
(CHEMBL2332858)
Show SMILES Brc1ccc(cc1)C(=O)Nc1ccc(Oc2ncnc3n[nH]cc23)cc1
Show InChI InChI=1S/C18H12BrN5O2/c19-12-3-1-11(2-4-12)17(25)23-13-5-7-14(8-6-13)26-18-15-9-22-24-16(15)20-10-21-18/h1-10H,(H,23,25)(H,20,21,22,24)
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Article
PubMed
n/an/a 7.47E+4n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...

J Med Chem 56: 1641-55 (2013)


Article DOI: 10.1021/jm301537p
BindingDB Entry DOI: 10.7270/Q29S1SC5
More data for this
Ligand-Target Pair