BDBM50429495 CHEMBL2332856

SMILES: FC(F)(F)c1ccc(cc1)C(=O)Nc1cccc(Oc2ncnc3n[nH]cc23)c1

InChI Key: InChIKey=RIGIEHDTVCPMDK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429495   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Danio rerio)	BDBM50429495 (CHEMBL2332856) Show SMILES FC(F)(F)c1ccc(cc1)C(=O)Nc1cccc(Oc2ncnc3n[nH]cc23)c1 Show InChI InChI=1S/C19H12F3N5O2/c20-19(21,22)12-6-4-11(5-7-12)17(28)26-13-2-1-3-14(8-13)29-18-15-9-25-27-16(15)23-10-24-18/h1-10H,(H,26,28)(H,23,24,25,27)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sichuan University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...				J Med Chem 56: 1641-55 (2013) Article DOI: 10.1021/jm301537p BindingDB Entry DOI: 10.7270/Q29S1SC5
					More data for this Ligand-Target Pair