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SMILES: Cc1cccc(NC(=O)Nc2ccc(Nc3ncnc4n[nH]cc34)cc2)c1C

InChI Key: InChIKey=VWCFFXCKCOGDHF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50429507   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Vascular endothelial growth factor receptor 2


(Danio rerio)		BDBM50429507
PNG
(CHEMBL2332843)
Show SMILES Cc1cccc(NC(=O)Nc2ccc(Nc3ncnc4n[nH]cc34)cc2)c1C
Show InChI InChI=1S/C20H19N7O/c1-12-4-3-5-17(13(12)2)26-20(28)25-15-8-6-14(7-9-15)24-18-16-10-23-27-19(16)22-11-21-18/h3-11H,1-2H3,(H2,25,26,28)(H2,21,22,23,24,27)
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Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Sichuan University

Curated by ChEMBL


Assay Description
Inhibition of VEGFR2 in transgenic zebrafish embryo assessed as inhibition of intersegmental vessels formation measured 33 hrs post fertilization by ...

J Med Chem 56: 1641-55 (2013)


Article DOI: 10.1021/jm301537p
BindingDB Entry DOI: 10.7270/Q29S1SC5
More data for this
Ligand-Target Pair