BDBM50429811 CHEMBL2337670
SMILES: CCOC(=O)C(=O)N(Cc1ccccc1)c1ccc2OC[C@H](COc3ccc(cc3)C(N)=[NH2+])Oc2c1
InChI Key: InChIKey=DYUYSOFSDYVVJJ-QFIPXVFZSA-O
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Prothrombin (Homo sapiens (Human)) | BDBM50429811 (CHEMBL2337670) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 78 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Inhibition of thrombin (unknown origin) using S-2238 as substrate preincubated with enzyme for 15 mins prior to substrate addition measured every 10 ... | Eur J Med Chem 62: 329-40 (2013) Article DOI: 10.1016/j.ejmech.2013.01.002 BindingDB Entry DOI: 10.7270/Q2445NTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Coagulation factor X (Homo sapiens (Human)) | BDBM50429811 (CHEMBL2337670) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Inhibition of factor 10a (unknown origin) using S-2222 as susbtrate preincubated with enzyme for 15 mins prior to substrate addition measured every 1... | Eur J Med Chem 62: 329-40 (2013) Article DOI: 10.1016/j.ejmech.2013.01.002 BindingDB Entry DOI: 10.7270/Q2445NTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ITGAV/ITGB3 (Homo sapiens (Human)) | BDBM50429811 (CHEMBL2337670) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Inhibition of biotinylated fibrinogen binding to human alphavbeta3 integrin receptor after 2 hrs by solid-phase competitive displacement assay | Eur J Med Chem 62: 329-40 (2013) Article DOI: 10.1016/j.ejmech.2013.01.002 BindingDB Entry DOI: 10.7270/Q2445NTR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Integrin alpha-IIb/beta-3 (Homo sapiens (Human)) | BDBM50429811 (CHEMBL2337670) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >2.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Inhibition of biotinylated fibrinogen binding to human GP 2b/3a after 2 hrs by solid-phase competitive displacement assay | Eur J Med Chem 62: 329-40 (2013) Article DOI: 10.1016/j.ejmech.2013.01.002 BindingDB Entry DOI: 10.7270/Q2445NTR | |||||||||||
More data for this Ligand-Target Pair |