BDBM50430181 CHEMBL2313136

SMILES: Oc1ccc(Cl)cc1C(=O)Nc1ccc(c(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=OAPJNIWWXJDUAC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50430181   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transmembrane protease serine 4 (Homo sapiens (Human))	BDBM50430181 (CHEMBL2313136) Show SMILES Oc1ccc(Cl)cc1C(=O)Nc1ccc(c(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C15H8ClF6NO2/c16-7-1-4-12(24)9(5-7)13(25)23-8-2-3-10(14(17,18)19)11(6-8)15(20,21)22/h1-6,24H,(H,23,25)	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Research Institute of Bioscience and Biotechnology Curated by ChEMBL					Assay Description Inhibition of N-terminal His6-tagged recombinant TMPRSS4 (unknown origin) fused with enterokinase cleavage sequence DYKDDDGDYKDDDDK expressed in Esch...				Bioorg Med Chem Lett 23: 1748-51 (2013) Article DOI: 10.1016/j.bmcl.2013.01.055 BindingDB Entry DOI: 10.7270/Q2057H8S
					More data for this Ligand-Target Pair