BDBM50430296 CHEMBL2333437

SMILES: CCc1ccc(cc1)-c1ccc2N(C)S(=O)(=O)c3cn(C)nc3-c2c1

InChI Key: InChIKey=JWHTYYABYMMKEE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50430296   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1 (Homo sapiens (Human))	BDBM50430296 (CHEMBL2333437) Show SMILES CCc1ccc(cc1)-c1ccc2N(C)S(=O)(=O)c3cn(C)nc3-c2c1 Show InChI InChI=1S/C19H19N3O2S/c1-4-13-5-7-14(8-6-13)15-9-10-17-16(11-15)19-18(12-21(2)20-19)25(23,24)22(17)3/h5-12H,4H2,1-3H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Allosteric inhibition of FAK (unknown origin) using poly-(GT)-biotin and 0.5 uM of ATP preincubated for 60 mins measured after 1 hr by HTRF assay				Bioorg Med Chem Lett 23: 1779-85 (2013) Article DOI: 10.1016/j.bmcl.2013.01.047 BindingDB Entry DOI: 10.7270/Q26Q1ZK9
					More data for this Ligand-Target Pair