BDBM50430354 CHEMBL2333900

SMILES: COc1ccc(cc1)[C@@H]1CN(Cc2ccccc2)C[C@H]1c1nc2ccc(cc2c(=O)[nH]1)-c1cn[nH]c1

InChI Key: InChIKey=OVLBSDJCLWRETA-IZZNHLLZSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50430354   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Rho-associated protein kinase 2 (Homo sapiens (Human))	BDBM50430354 (CHEMBL2333900) Show SMILES COc1ccc(cc1)[C@@H]1CN(Cc2ccccc2)C[C@H]1c1nc2ccc(cc2c(=O)[nH]1)-c1cn[nH]c1 |r| Show InChI InChI=1S/C29H27N5O2/c1-36-23-10-7-20(8-11-23)25-17-34(16-19-5-3-2-4-6-19)18-26(25)28-32-27-12-9-21(22-14-30-31-15-22)13-24(27)29(35)33-28/h2-15,25-26H,16-18H2,1H3,(H,30,31)(H,32,33,35)/t25-,26+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Translational Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant 6-His-tagged ROCK2 expressed in baculovirus-infected Sf9 cells using LCB-AKRRRLSSLRA-NH2 as substrate after 25 mins b...				Bioorg Med Chem Lett 23: 1592-9 (2013) Article DOI: 10.1016/j.bmcl.2013.01.109 BindingDB Entry DOI: 10.7270/Q2TD9ZQM
					More data for this Ligand-Target Pair