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SMILES: COc1cccc(Nc2nc(N)nc3[nH]c4cccc(Cl)c4c23)c1

InChI Key: InChIKey=WAXJONPSDKJXDR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50430567   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50430567 (CHEMBL2337366) Show SMILES COc1cccc(Nc2nc(N)nc3[nH]c4cccc(Cl)c4c23)c1 Show InChI InChI=1S/C17H14ClN5O/c1-24-10-5-2-4-9(8-10)20-15-14-13-11(18)6-3-7-12(13)21-16(14)23-17(19)22-15/h2-8H,1H3,(H4,19,20,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta in human SF539 cells assessed as inhibition of PDGFR-BB-induced tyrosine phosphorylation incubated for 60 mins prior to EGF-a...				Bioorg Med Chem 21: 1857-64 (2013) Article DOI: 10.1016/j.bmc.2013.01.040 BindingDB Entry DOI: 10.7270/Q2NS0W97
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50430567 (CHEMBL2337366) Show SMILES COc1cccc(Nc2nc(N)nc3[nH]c4cccc(Cl)c4c23)c1 Show InChI InChI=1S/C17H14ClN5O/c1-24-10-5-2-4-9(8-10)20-15-14-13-11(18)6-3-7-12(13)21-16(14)23-17(19)22-15/h2-8H,1H3,(H4,19,20,21,22,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of VEGFR2 in human U251 cells assessed as inhibition of VEGF-induced tyrosine phosphorylation incubated for 60 mins prior to VEGF-activati...				Bioorg Med Chem 21: 1857-64 (2013) Article DOI: 10.1016/j.bmc.2013.01.040 BindingDB Entry DOI: 10.7270/Q2NS0W97
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50430567 (CHEMBL2337366) Show SMILES COc1cccc(Nc2nc(N)nc3[nH]c4cccc(Cl)c4c23)c1 Show InChI InChI=1S/C17H14ClN5O/c1-24-10-5-2-4-9(8-10)20-15-14-13-11(18)6-3-7-12(13)21-16(14)23-17(19)22-15/h2-8H,1H3,(H4,19,20,21,22,23)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
Duquesne University Curated by ChEMBL					Assay Description Inhibition of EGFR in human A431 cells assessed as inhibition of EGF-induced tyrosine phosphorylation incubated for 60 mins prior to EGF-activation m...				Bioorg Med Chem 21: 1857-64 (2013) Article DOI: 10.1016/j.bmc.2013.01.040 BindingDB Entry DOI: 10.7270/Q2NS0W97
					More data for this Ligand-Target Pair