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SMILES: Nc1nc(Nc2ccccc2)c2c(n1)[nH]c1ccccc21

InChI Key: InChIKey=QQJZIMVTIBWSMO-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50430573   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Epidermal growth factor receptor


(Homo sapiens (Human))		BDBM50430573
PNG
(CHEMBL2337373)
Show SMILES Nc1nc(Nc2ccccc2)c2c(n1)[nH]c1ccccc21
Show InChI InChI=1S/C16H13N5/c17-16-20-14(18-10-6-2-1-3-7-10)13-11-8-4-5-9-12(11)19-15(13)21-16/h1-9H,(H4,17,18,19,20,21)
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KEGG

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Similars
Article
PubMed
n/an/a 147n/an/an/an/an/an/a



Duquesne University

Curated by ChEMBL


Assay Description
Inhibition of EGFR in human A431 cells assessed as inhibition of EGF-induced tyrosine phosphorylation incubated for 60 mins prior to EGF-activation m...

Bioorg Med Chem 21: 1857-64 (2013)


Article DOI: 10.1016/j.bmc.2013.01.040
BindingDB Entry DOI: 10.7270/Q2NS0W97
More data for this
Ligand-Target Pair