BDBM50430847 CHEMBL2336009

SMILES: CN1CCN(Cc2cc(C)cc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4ccnn4c3)c2)CC1

InChI Key: InChIKey=CZCBVFVSSWZKPW-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50430847   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50430847 (CHEMBL2336009) Show SMILES CN1CCN(Cc2cc(C)cc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4ccnn4c3)c2)CC1 Show InChI InChI=1S/C29H30N6O/c1-21-14-24(19-34-12-10-33(3)11-13-34)16-27(15-21)32-29(36)26-6-4-22(2)25(17-26)7-5-23-18-30-28-8-9-31-35(28)20-23/h4,6,8-9,14-18,20H,10-13,19H2,1-3H3,(H,32,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	274	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of c-KIT (unknown origin) using Ser/Thr 6 peptide as substrate incubated for 1 hr prior to substrate addition measured after 2 hrs by FRET...				J Med Chem 56: 3281-95 (2013) Article DOI: 10.1021/jm301824k BindingDB Entry DOI: 10.7270/Q22V2HHJ
					More data for this Ligand-Target Pair
Discoidin domain-containing receptor 2 (Homo sapiens (Human))	BDBM50430847 (CHEMBL2336009) Show SMILES CN1CCN(Cc2cc(C)cc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4ccnn4c3)c2)CC1 Show InChI InChI=1S/C29H30N6O/c1-21-14-24(19-34-12-10-33(3)11-13-34)16-27(15-21)32-29(36)26-6-4-22(2)25(17-26)7-5-23-18-30-28-8-9-31-35(28)20-23/h4,6,8-9,14-18,20H,10-13,19H2,1-3H3,(H,32,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DDR2 (unknown origin) using fluorescein-labeled poly GAT as substrate incubated for 1 hr prior to substrate addition measured after 1 h...				J Med Chem 56: 3281-95 (2013) Article DOI: 10.1021/jm301824k BindingDB Entry DOI: 10.7270/Q22V2HHJ
					More data for this Ligand-Target Pair
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human))	BDBM50430847 (CHEMBL2336009) Show SMILES CN1CCN(Cc2cc(C)cc(NC(=O)c3ccc(C)c(c3)C#Cc3cnc4ccnn4c3)c2)CC1 Show InChI InChI=1S/C29H30N6O/c1-21-14-24(19-34-12-10-33(3)11-13-34)16-27(15-21)32-29(36)26-6-4-22(2)25(17-26)7-5-23-18-30-28-8-9-31-35(28)20-23/h4,6,8-9,14-18,20H,10-13,19H2,1-3H3,(H,32,36)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of DDR1 (unknown origin) using fluorescein-labeled poly GAT as substrate incubated for 1 hr prior to substrate addition measured after 1 h...				J Med Chem 56: 3281-95 (2013) Article DOI: 10.1021/jm301824k BindingDB Entry DOI: 10.7270/Q22V2HHJ
					More data for this Ligand-Target Pair