null
SMILES: Cc1cccc(NC(=O)c2ccc(C)c(c2)C#Cc2cnc3ccnn3c2)c1
InChI Key: InChIKey=FLOSOQYXYAJVAG-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Epithelial discoidin domain-containing receptor 1 (Homo sapiens (Human)) | BDBM50430868 (CHEMBL2331602) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of DDR1 (unknown origin) using fluorescein-labeled poly GAT as substrate incubated for 1 hr prior to substrate addition measured after 1 h... | J Med Chem 56: 3281-95 (2013) Article DOI: 10.1021/jm301824k BindingDB Entry DOI: 10.7270/Q22V2HHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human)) | BDBM50430868 (CHEMBL2331602) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of c-KIT (unknown origin) using Ser/Thr 6 peptide as substrate incubated for 1 hr prior to substrate addition measured after 2 hrs by FRET... | J Med Chem 56: 3281-95 (2013) Article DOI: 10.1021/jm301824k BindingDB Entry DOI: 10.7270/Q22V2HHJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Discoidin domain-containing receptor 2 (Homo sapiens (Human)) | BDBM50430868 (CHEMBL2331602) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of DDR2 (unknown origin) using fluorescein-labeled poly GAT as substrate incubated for 1 hr prior to substrate addition measured after 1 h... | J Med Chem 56: 3281-95 (2013) Article DOI: 10.1021/jm301824k BindingDB Entry DOI: 10.7270/Q22V2HHJ | |||||||||||
More data for this Ligand-Target Pair |