BDBM50430977 CHEMBL2337869

SMILES: Cc1ccc(cc1)-c1ccc(Cn2cccc(O)c2=S)cc1

InChI Key: InChIKey=QBARVXAQLMAXTF-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50430977   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50430977 (CHEMBL2337869) Show SMILES Cc1ccc(cc1)-c1ccc(Cn2cccc(O)c2=S)cc1 Show InChI InChI=1S/C19H17NOS/c1-14-4-8-16(9-5-14)17-10-6-15(7-11-17)13-20-12-2-3-18(21)19(20)22/h2-12,21H,13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	454	n/a	n/a	n/a	n/a	n/a	25
Georgia Tech Research Corporation US Patent					Assay Description Fluor de Lys is a fluorescence based HDAC activity assay comprising a combination of fluorogenic Histone deAcetylase Lysyl substrate and a developer....				US Patent US8871728 (2014) BindingDB Entry DOI: 10.7270/Q29885R4
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50430977 (CHEMBL2337869) Show SMILES Cc1ccc(cc1)-c1ccc(Cn2cccc(O)c2=S)cc1 Show InChI InChI=1S/C19H17NOS/c1-14-4-8-16(9-5-14)17-10-6-15(7-11-17)13-20-12-2-3-18(21)19(20)22/h2-12,21H,13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) after 60 mins by SAMDI spectrophotometric analysis				J Med Chem 56: 3492-506 (2013) Article DOI: 10.1021/jm301769u BindingDB Entry DOI: 10.7270/Q29C6ZSC
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM50430977 (CHEMBL2337869) Show SMILES Cc1ccc(cc1)-c1ccc(Cn2cccc(O)c2=S)cc1 Show InChI InChI=1S/C19H17NOS/c1-14-4-8-16(9-5-14)17-10-6-15(7-11-17)13-20-12-2-3-18(21)19(20)22/h2-12,21H,13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	454	n/a	n/a	n/a	n/a	n/a	n/a
Georgia Institute of Technology Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) after 60 mins by SAMDI spectrophotometric analysis				J Med Chem 56: 3492-506 (2013) Article DOI: 10.1021/jm301769u BindingDB Entry DOI: 10.7270/Q29C6ZSC
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50430977 (CHEMBL2337869) Show SMILES Cc1ccc(cc1)-c1ccc(Cn2cccc(O)c2=S)cc1 Show InChI InChI=1S/C19H17NOS/c1-14-4-8-16(9-5-14)17-10-6-15(7-11-17)13-20-12-2-3-18(21)19(20)22/h2-12,21H,13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	25
Georgia Tech Research Corporation US Patent					Assay Description Fluor de Lys is a fluorescence based HDAC activity assay comprising a combination of fluorogenic Histone deAcetylase Lysyl substrate and a developer....				US Patent US8871728 (2014) BindingDB Entry DOI: 10.7270/Q29885R4
					More data for this Ligand-Target Pair