BDBM50431017 CHEMBL2338327

SMILES: OC(=O)[C@@H](Cc1ccccc1)NC(=O)c1nc(Cl)c2ccccc2c1O

InChI Key: InChIKey=QZRXYSFKUSQNIL-CQSZACIVSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431017   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens (Human))	BDBM50431017 (CHEMBL2338327) Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)c1nc(Cl)c2ccccc2c1O |r| Show InChI InChI=1S/C19H15ClN2O4/c20-17-13-9-5-4-8-12(13)16(23)15(22-17)18(24)21-14(19(25)26)10-11-6-2-1-3-7-11/h1-9,14,23H,10H2,(H,21,24)(H,25,26)/t14-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...				J Med Chem 56: 3680-8 (2013) Article DOI: 10.1021/jm400193d BindingDB Entry DOI: 10.7270/Q21V5GBQ
					More data for this Ligand-Target Pair