BDBM50431019 CHEMBL2338325

SMILES: OC(=O)CNC(=O)c1ncc(cc1O)-c1ccc2cc(O)ccc2c1

InChI Key: InChIKey=ITDVLBGAPZAPRP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431019   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens (Human))	BDBM50431019 (CHEMBL2338325) Show SMILES OC(=O)CNC(=O)c1ncc(cc1O)-c1ccc2cc(O)ccc2c1 Show InChI InChI=1S/C18H14N2O5/c21-14-4-3-10-5-11(1-2-12(10)6-14)13-7-15(22)17(19-8-13)18(25)20-9-16(23)24/h1-8,21-22H,9H2,(H,20,25)(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...				J Med Chem 56: 3680-8 (2013) Article DOI: 10.1021/jm400193d BindingDB Entry DOI: 10.7270/Q21V5GBQ
					More data for this Ligand-Target Pair