BDBM50431020 CHEMBL2030875

SMILES: OC(=O)[C@H](CSCc1ccc2ccccc2c1)NC(=O)c1ncccc1O

InChI Key: InChIKey=ATHOTSVECZJAJD-INIZCTEOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50431020   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-ketoglutarate-dependent dioxygenase FTO (Homo sapiens (Human))	BDBM50431020 (CHEMBL2030875) Show SMILES OC(=O)[C@H](CSCc1ccc2ccccc2c1)NC(=O)c1ncccc1O |r| Show InChI InChI=1S/C20H18N2O4S/c23-17-6-3-9-21-18(17)19(24)22-16(20(25)26)12-27-11-13-7-8-14-4-1-2-5-15(14)10-13/h1-10,16,23H,11-12H2,(H,22,24)(H,25,26)/t16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...				J Med Chem 56: 3680-8 (2013) Article DOI: 10.1021/jm400193d BindingDB Entry DOI: 10.7270/Q21V5GBQ
					More data for this Ligand-Target Pair